What is Cenforce 120 Mg
Cenforce 120 Mg contains Sildenafil Citrate as an active agent which is used to treat Erectile Dysfunction and Pulmonary Hypertension. You may purchase this prescription based drug from any of the leading online pharmacy stores, drugstores and medical supply stores only on doctor prescription.
Cenforce contains an active ingredient Sildenafil which is FDA-approved medication used to treat erectile dysfunction problems in men. After being introduced in 1998, It’s become the most popular treatment for erectile dysfunction issues. It is a fast-acting medication that can last up to four hours. It works well for men at any age, regardless of how long the patient has been having issues getting and maintaining an erection.
It has been estimated that around 140 million men worldwide suffer from impotence. Over half of all men with impotence are thought to have some physical (medical) cause. The remainder is believed to have psychogenic causes of impotence. Medical causes of impotence include diabetes and circulatory, neurological, or urological conditions.
Cenfore 120 Mg Mode of action
The physiological mechanism responsible for erection of the penis involves the release of nitric oxide (NO) in the corpus cavernosum in response to sexual stimulation. Nitric oxide then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
Cenforce 120 Mg has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of NO by inhibiting PDE5, which is responsible for the biodegradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by Cenforce 120 Mg produces increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and increased inflow of blood to the corpus cavernosum. Sildenafil, at recommended doses, has no effect in the absence of sexual stimulation.
Cenforce 120 Mg side effects
Given below are the common side effects of Cenforce 12o Mg.
- Nasal Congestion
- Abnormal vision (aka “blue-tinted” vision)
- Back pain
- Muscle pain
Serious Viagra Side Effects
Serious, but less common, side effects of Cenforce 120 Mg include:
- Sudden loss of vision in one or both eyes
- Sudden decrease or loss of hearing
- An erection lasting longer than 4 hours (priapism)
Who Should Not Take Viagra?
Do NOT take Cenforce 120 Mg if you:
- Take nitrates for a cardiac condition
- Take riociguat for pulmonary arterial hypertension
- Are allergic to sildenafil or any of the inactive ingredients in Viagra
- Are not healthy enough for sex
Cenforce 120 Mg drug interactions.
Sildenafil, a recently approved drug, should not be used by people who are using organic nitrates, blood pressure medications, or certain HIV medications. Some protease inhibitors can increase sildenafil citrate levels in the blood. Drugs such as efavirenz and Nevirapine can reduce sildenafil levels. Other drugs and their effects are discussed.
- Potential low blood pressure triggers:
- Flomax (Boehringer Ingelheim)
- Potential toxicity:
- Reyataz (Bristol-Myers Squibb)
- Grapefruit juice
- Diflucan (Pfizer)
- Gleevec (Novartis)
- Crixivan (Merck)
- Tykerb (GlaxoSmithKline)
- Mifeprex (Danco Labs)
- Viracept (Pfizer)
- Ketek (Sanofi-Aventis)
- Potential Inhibitors:
- Sustiva (BMS)
- Provigil (Cephalon)
- Viramune (Boehringer)